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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK7
All Species:
13.64
Human Site:
S127
Identified Species:
23.08
UniProt:
Q8WTQ7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTQ7
NP_631948.1
553
62212
S127
G
N
P
Q
P
F
L
S
Q
A
V
A
T
K
C
Chimpanzee
Pan troglodytes
XP_526333
553
62171
R127
G
N
P
Q
P
F
L
R
Q
A
V
A
T
K
C
Rhesus Macaque
Macaca mulatta
XP_001112570
553
62224
S127
G
N
P
H
P
F
F
S
Q
A
M
A
T
K
C
Dog
Lupus familis
XP_542813
553
62196
S127
G
H
P
H
P
F
L
S
P
A
L
A
T
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEB1
590
67714
Q123
V
F
I
A
Q
V
G
Q
D
L
V
S
Q
T
E
Rat
Rattus norvegicus
Q62833
590
67764
S127
Q
V
G
Q
D
L
V
S
Q
T
E
K
K
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
E128
L
F
C
G
F
L
E
E
E
T
V
R
A
V
E
Chicken
Gallus gallus
XP_426681
551
62925
S126
N
Y
L
S
F
M
S
S
D
L
V
S
K
C
Q
Frog
Xenopus laevis
NP_001131051
551
62674
K127
G
S
L
N
F
L
G
K
D
L
S
S
R
I
Q
Zebra Danio
Brachydanio rerio
NP_001027011
549
62214
T123
K
S
S
L
T
F
L
T
G
D
V
A
T
K
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
D247
L
V
L
D
V
L
N
D
D
L
I
A
Q
V
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
W129
S
Q
D
E
Q
E
F
W
C
S
F
L
S
D
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42818
465
52569
S88
T
L
L
E
T
E
D
S
I
D
L
V
E
C
L
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
I327
K
N
D
S
S
H
P
I
W
H
H
K
T
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.9
85.7
N.A.
41.8
42.2
N.A.
47.9
72.8
68.7
60.2
N.A.
38.2
N.A.
39.4
N.A.
Protein Similarity:
100
99.4
98
92.7
N.A.
60.6
60.6
N.A.
65.8
84.2
82.8
75.9
N.A.
54.3
N.A.
57.6
N.A.
P-Site Identity:
100
93.3
80
73.3
N.A.
6.6
20
N.A.
6.6
13.3
6.6
46.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
93.3
86.6
86.6
N.A.
13.3
26.6
N.A.
13.3
20
20
60
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
29
0
43
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
0
0
0
15
36
% C
% Asp:
0
0
15
8
8
0
8
8
29
15
0
0
0
8
0
% D
% Glu:
0
0
0
15
0
15
8
8
8
0
8
0
8
0
22
% E
% Phe:
0
15
0
0
22
36
15
0
0
0
8
0
0
0
8
% F
% Gly:
36
0
8
8
0
0
15
0
8
0
0
0
0
0
0
% G
% His:
0
8
0
15
0
8
0
0
0
8
8
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
8
0
8
0
0
8
0
% I
% Lys:
15
0
0
0
0
0
0
8
0
0
0
15
15
36
0
% K
% Leu:
15
8
29
8
0
29
29
0
0
29
15
8
0
8
15
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
29
0
8
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
29
0
29
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
8
8
0
22
15
0
0
8
29
0
0
0
15
0
15
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
8
% R
% Ser:
8
15
8
15
8
0
8
43
0
8
8
22
8
0
0
% S
% Thr:
8
0
0
0
15
0
0
8
0
15
0
0
43
15
0
% T
% Val:
8
15
0
0
8
8
8
0
0
0
43
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _